seroprevalence of hepatitis c in hemophilia patients refering to iran hemophilia society center in tehran
نویسندگان
چکیده
background: hemophilia is a congenital disease resulting in deficiency of clotting factors. for this reason they have a constant need of clotting factors which makes them one of the largest consumers of blood products. through this blood product use, many of these patients have become infected by hepatitis c virus (hcv). we have studied the seroprevalence of anti-hcv antibody and hcv infection in hemophilic patients refereeing to iran hemophilia society center in tehran. materials and methods: in a cross-sectional study we reviewed files of all hemophilic patients registered in iran hemophilia society center in tehran from 2003 to 2005. subjects with available results of anti-hcv antibody were included. results : among the 1170 files examined, 1095 contained data on hcv infection status. from these, 802 subjects (72.3%) had anti-hcv antibodies. genotype 1 was most common (60%) followed by genotype 3 (38%). almost 10% of patients with anti-hcv antibodies had a negative hcv rna by pcr. conclusions: hcv is very common among hemophilic patients and considering the risk for the patients and their contacts it is necessary to screen all hemophiliacs for hcv and treat if indicated.
منابع مشابه
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گوارشجلد ۱۶، شماره ۳، صفحات ۱۶۹-۰
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